Breakthrough Studies in Stem Cell & Exosome Therapy
Explore a curated selection of peer-reviewed studies from leading researchers and medical experts at the forefront of regenerative medicine. These publications highlight groundbreaking advancements in stem cell therapy, tissue engineering, and gene therapies, offering valuable insights into the evolving landscape of innovative healthcare solutions.
Osteoarthritis (OA)
Discover how mesenchymal stem cells (MSCs) are advancing regenerative medicine, specifically in the areas of articular cartilage and intervertebral disc repair.
Traumatic Brain Injury (TBI)
Umbilical cord mesenchymal stem cell transplantation significantly enhances neurological function in patients with traumatic brain injury sequelae.
Autism
Autologous Cord Blood Infusions Prove Safe and Feasible for Young Children with Autism Spectrum Disorder: Findings from a Single-Center Phase I Open-Label Trial
Rheumatoid Arthritis/ Polymyalgia Rheumatica (OA/PMR)
Autologous Stromal Vascular Fraction Cells: A Potential Tool for Promoting Tolerance in Rheumatic Diseases.
Post Cancer Chemotherapy
Adult Mesenchymal Stem Cells in the Treatment of Radiation Injury
Anti-Aging
Cellular Reprogramming-Based Strategies for Anti-Aging
Osteoarthritic Joint Pain
Kon E, et al. (2010) Platelet-rich plasma: intra-articular knee injections produced favorable results on degenerative cartilage lesions. Link
Khoshbin A, et al. (2013) The efficacy of platelet-rich plasma in the treatment of symptomatic knee osteoarthritis: a systematic review with quantitative synthesis. Link
Sánchez M, et al. (2012) Ultrasound-guided platelet-rich plasma injections for the treatment of osteoarthritis of the hip. Link
Centeno C, et al. (2016) A dose response analysis of a specific bone marrow concentrate treatment protocol for knee osteoarthritis. Link
In Conjunction with Surgical Treatment
Fortier LA, et al. (2010) Concentrated bone marrow aspirate improves full-thickness cartilage repair compared with microfracture in an equine model. Link
Milano G, et al. (2010) The effect of platelet rich plasma combined with microfractures on the treatment of chondral defects: an experimental study in a sheep model. Link
Buda R, et al. (2015) One-step bone marrow-derived cell transplantation in talar osteochondral lesions: mid-term results. Link
Meniscus or Ligament Injuries
Meniscus or Ligament Injuries
Foster TE, et al. (2009) Platelet-rich plasma: from basic science to clinical application. Link
Murray MM, et al. (2009) Enhanced histologic repair in a central wound in the anterior cruciate ligament with a collagen–platelet-rich plasma scaffold. Link
Braun HJ, et al. (2013) The Use of PRP in ligament and meniscal healing. Link
Yu H, et al. (2015) Meniscus repair using mesenchymal stem cells – a comprehensive review. Link
Cook JL, et al. (2016) Multiple injections of leukoreduced platelet rich plasma reduce pain and functional impairment in a canine model of ACL and meniscal deficiency. Link
Muscle and Tendon InjuriesLateral Epicondylitis
Peerbooms JC, (2010) Positive effect of an autologous platelet concentrate in lateral epicondylitis in a double-blind randomized controlled trial: platelet-rich plasma versus corticosteroid injection with a 1-Year follow-up. Link
Gosens T, et al. (2011) Ongoing positive effect of platelet-rich plasma versus corticosteroid injection in lateral epicondylitis: a double-blind randomized controlled trial with 2-year follow-up. Link
Mishra A, et al. (2014) Efficacy of platelet-rich plasma for chronic tennis elbow: a double-blind, prospective, multicenter, randomized controlled trial of 230 patients. Link
Patellar Tendonitis
Cervellin M, et al. (2012) Autologous platelet-rich plasma gel to reduce donor-site morbidity after patellar tendon graft harvesting for anterior cruciate ligament reconstruction: a randomized, controlled clinical study. Link
Di Matteo B, et al. (2015) Platelet-rich plasma: evidence for the treatment of patellar and Achilles tendinopathy—a systematic review. Link
Pascual-Garrido C, et al. (2012) Treatment of chronic patellar tendinopathy with autologous bone marrow stem cells: a 5-year followup. Link
Rotator Cuff Tears
Randelli P, et al. (2011) Platelet rich plasma in arthroscopic rotator cuff repair: a prospective RCT study, 2-year follow-up. Link
Hernigou P, et al. (2014) Biologic augmentation of rotator cuff repair with mesenchymal stem cells during arthroscopy improves healing and prevents further tears: a case-controlled study. Link
Fractures
Galasso O, et al. (2008) Expandable intramedullary nailing and platelet rich plasma to treat long bone non-unions. Link
Bursitis
Sampson S, et al. (2008) Platelet rich plasma injection grafts for musculoskeletal injuries: a review. Link
Cosmetic Surgery
Man D, et al. (2001) The use of autologous platelet-rich plasma (platelet gel) and autologous platelet-poor plasma (fibrin glue) in cosmetic surgery. Link
Cervelli V, et al. (2009) Application of platelet-rich plasma in plastic surgery: clinical and in-vitro evaluation. Link
Redaelli A, et al. (2010) Face and neck revitalization with platelet-rich plasma (PRP): clinical outcome in a series of 23 consecutively treated patients. Link
Sclafani AP, and SA McCormick. (2012) Induction of dermal collagenesis, angiogenesis, and adipogenesis in human skin by injection of platelet-rich fibrin matrix. Link
Lee JW, et al. (2011) The Efficacy of autologous platelet rich plasma combined with ablative carbon dioxide fractional resurfacing for acne scars: A Simultaneous Split-Face Trial. Link
Cho JM, et al. (2011) Effect of platelet-rich plasma on ultraviolet b-induced skin wrinkles in nude mice. Link
Shin MK, et al. (2012) Platelet-rich plasma combined with fractional laser therapy for skin rejuvenation. Link
Spine
Pettine K, et al. (2015) Percutaneous Injection of Autologous Bone Marrow Concentrate Cells Significantly Reduces Lumbar Discogenic Pain Through 12 Months. Link
Pettine K, et al. (2016) Treatment of discogenic back pain with autologous bone marrow concentrate injection with minimum two year follow-up. Link
Monfett M, et al. (2016) Intradiscal platelet-rich plasma (PRP) injections for discogenic low back pain: an update. Link
Wound Care
Hom DB, et al. (2007) The healing effects of autologous platelet gel on acute human skins wounds. Link
Driver VR, et al. (2006) A prospective, randomized, controlled trial of autologous platelet-rich plasma gel for the treatment of diabetic foot ulcers. Link
Kazakos K, et al. (2009) The use of autologous PRP gel as an aid in the management of trauma wounds. Link
Carter MJ, et al. (2011) Use of platelet-rich plasma gel on wound healing: a systematic review and meta-analysis. Link
Saad Setta, H, et al. (2011) Platelet-rich plasma versus platelet-poor plasma in the management of chronic diabetic foot ulcers: a comparative study. Link
Dabiri G, et al. (2013) The emerging use of bone marrow-derived mesenchymal stem cells in the treatment of human chronic wounds. Link
Oral and Maxillofacial Surgery
Marx RE. Platelet-rich plasma: evidence to support its use. Link
Sammartino G, et al. (2005) Use of autologous platelet-rich plasma in periodontal defect treatment after extraction of impacted mandibular third molars. Link
Bajaj P, et al. (2013) Comparative evaluation of autologous platelet-rich fibrin and platelet-rich plasma in the treatment of mandibular degree II furcation defects: a randomized controlled clinical trial. Link
Peripheral Vascular Disease
Tateishi-Yuyama E, et al. (2002) Therapeutic angiogenesis for patients with limb ischemia by autologous transplantation of bone-marrow cells: a pilot study and a randomized controlled trial. Link
Bartsch T, et al. (2007) Transplantation of autologous mononuclear bone marrow stem cells in patients with peripheral arterial disease (the TAM-PAD study). Link
Amann B, et al. (2009) Autologous bone marrow cell transplantation increases leg perfusion and reduces amputations in patients with advanced critical limb ischemia due to peripheral artery disease. Link
Fadnini GP, et al. (2010) Autologous stem cell therapy for peripheral arterial disease: Meta-analysis and systemic review of the literature. Link
Molavi B, et al. (2016) Safety and Efficacy of Repeated Bone Marrow Mononuclear Cell Therapy in Patients with Critical Limb Ischemia in a Pilot Randomized Controlled Trial. Link
FAQ
HOW IV HYDRATION WORKS
HOW DO IV DRIPS WORK?
A catheter and a saline-based electrolyte solution are used in an IV fluid drip to deliver selected vitamins and nutrients directly into the bloodstream, bypassing the digestive tract. This process allows for instant availability of the nutrition to address the body's health needs. Compared to consuming vitamins or medications in liquid or pill form, administering them through an IV is more effective. Ingested nutrients must first pass through the digestive system and get broken down before reaching the cells that require them.
Our certified nurses administer our therapies to clients in their desired locations, such as their homes, offices, or hotels. We have a network of licensed and insured nurse practitioners and registered nurses who possess extensive medical backgrounds in emergency rooms, operating rooms, and ICUs, and are highly skilled in IV therapy.
Our IV infusions are made up of essential fluids, electrolytes, vitamins, and antioxidants that help quickly address a variety of conditions and promote overall body health. They are designed to assist with hangovers, dehydration, jet lag, exhaustion, athletic fatigue, and more.
WHO IS A GOOD CANDIDATE FOR IV THERAPY?
IV hydration provides healing benefits that can help boost the immune system, replenish lost nutrients, and improve overall wellbeing. While the body requires a certain amount of vitamins and minerals to function properly, most people don't consume an optimal level of nutrients through their diet. Physicians have used IV therapy for many years to bridge this gap safely and improve the health of patients with few risks or side effects. In addition to feeling better after an IV infusion, some cocktails can also provide relief from symptoms of ailments like fibromyalgia, migraines, or asthma.
IV hydration can be a valuable addition to a personal wellness plan, regardless of whether you have specific concerns or simply want to feel healthier and more energized. Our team can develop customized treatments tailored to your unique needs, incorporating precise combinations of nutrients to help you feel your best self. IV therapy is effective for patients with varied wellness goals and can be used either as a single treatment or integrated into a regular routine.
It's worth noting that IV hydration isn't solely for those who are unwell; it can be beneficial to anyone seeking to improve their overall wellbeing.
WHAT GOES INTO AN IV?
Each concoction differs depending on the health and wellness needs of each patient. The most common ingredients that go into IV's include:
Saline. This a solution of salt in water and is the most common type of fluid for IV's. A Saline solution is great for dehydration and hangovers since sodium is a type of electrolyte.
Vitamins. The benefits of vitamins and antioxidants are essential, as they can give us a boost of energy, strengthen our immune system, plus so much more.
Electrolytes. These essential elements and compounds hydrate our bodies, regulate nerve and muscle function, regulate blood pressure, and more. Besides sodium, your body needs potassium, calcium, bicarbonate, magnesium, chloride and phosphate — all of which are electrolytes.
IS IV HYDRATION SAFE?
IV hydration is a safe procedure that involves the administration of FDA-approved vitamins that have undergone rigorous testing before being offered to clients. A registered nurse administers all IV drips under the guidance of a medical director, and a client's health history is evaluated before the procedure. While side effects from IV hydration are typically mild or nonexistent, some discomfort, itching, bruising, redness, or inflammation at the injection site may occur and could last from a few minutes to several days. True allergic reactions to IV hydration are very rare.
HOW OFTEN SHOULD I GET AN IV?
Our recommendation for clients seeking IV hydration is to receive the treatment at least 1-2 times per month. However, we understand that each person has unique needs, and our approach is tailored accordingly. For those focused on maintaining their overall health and well-being, we suggest two IV drips per month, as this can help address any potential vitamin deficiencies and promote balance.